Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus
نویسندگان
چکیده
منابع مشابه
Virus-Induced Gene Silencing, a Post Transcriptional Gene Silencing Method
Virus-induced gene silencing (VIGS) is one of the reverse genetics tools for analysis of gene function that uses viral vectors carrying a target gene fragment to produce dsRNA which trigger RNA-mediated gene silencing. There are a number of viruses which have been modified to silence the gene of interest effectively with a sequence-specific manner. Therefore, different types of methodologies ha...
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genic bacterium notorious for its ability to redirect the plant metabolism to meet the pathogen’s gourmandise. This is achieved by the stable genetic modification of the host plant after integration of the bacterial T-DNA into the plant genome, a unique example of interkingdom DNA transfer. The T-DNA stems from the bacterial tumor-inducing (Ti) plasmid and travels as a single-stranded molecule ...
متن کاملPost-transcriptional gene silencing in plants
Epigenetic regulation of gene expression is a heritable change in gene expression that cannot be explained by changes in gene sequence. It can result in the repression or activation of gene expression and is therefore referred to as gene silencing or gene activation respectively. Until the end of the 1980s, only modifications of DNA or protein that lead to transcriptional repression or activati...
متن کاملMechanistic Characterization of Post-transcriptional Gene Silencing
With the ongoing task of identifying and characterizing genes in the human genome, there is a great demand for tools to study these genes. Today, reverse genetics is the most effective way to explore gene function. This involves suppression of the gene of interest by a set of manipulation techniques. In addition to this, many conditions like viral infections, cancers and cardio-vascular disease...
متن کاملPost-transcriptional gene silencing in plants.
Overexpression of chimeric transgenes in plants can trigger post-transcriptional gene silencing that is dependent on epigenetic information and physiological conditions. The current view is that unproductive RNA serves as a crucial signal for gene silencing, although direct evidence is lacking for this theory. A signalling cascade then leads to strongly enhanced turnover of all RNAs that share ...
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ژورنال
عنوان ژورنال: World Journal of Virology
سال: 2015
ISSN: 2220-3249
DOI: 10.5501/wjv.v4.i3.219